联系我们
地址:北京市海淀区中关村北一街2号
中国科学院化学研究所3号楼
邮编:100190
Tel: +86-10-82614087
Fax: +86-10-82612629
Email: jbli@iccas.ac.cn
科研动态
"General and Versatile Nanoarchitectonics for Amino Acid-Based Glasses via Co-Assembly of Organic Counterions"
Angew. Chem. Int. Ed., 2025, e202422272.
"Reduction of CO2 Accompanying ATP Synthesis in Polydopamine Microreactors Covered by Lipid Bilayers with ATPase"
Angew. Chem. Int. Ed., 2025, e202509835.
"A Photophosphorylation Nanobot for Restoring Anabolism of Myocardial Injury"
J. Am. Chem. Soc., 2025, DOI: 10.1021/jacs.5c05904.
"Immunostimulatory Hydrogel with Synergistic Blockage of Glutamine Metabolism and Chemodynamic Therapy for Postoperative Management of Glioblastoma"
Adv. Sci., 2025, 2412507.
"Chiroptical Switching and Strong Circularly Polarized Luminescence in Peptide Supramolecular Assemblies"
Nat. Commun., 2025,DOI: 10.1038/s41467-025-61007-6.
"A Well-Coupled Supramolecular System Accelerates Photophosphorylation"
Angew. Chem. Int. Ed., 2024, e202417474.
" Nanoarchitectonics of Vesicle Microreactors for Oscillating ATP Synthesis and Hydrolysis"
Angew. Chem. Int. Ed., 2024, e202411981.
" Artificial Mitochondria Nanoarchitectonics via a Supramolecular Assembled Microreactor Covered by ATP Synthase"
Angew. Chem. Int. Ed., 2024, e202411164.
" Nanoarchitectonics with a Membrane-Embedded Electron Shuttle Mimics the Bioenergy Anabolism of Mitochondria"
Angew. Chem. Int. Ed., 2024, e202319116.
" Photozyme-Catalyzed ATP Generation Based on ATP Synthase-Reconstituted Nanoarchitectonics"
J. Am. Chem. Soc., 2023, 145, 20907−20912.
" CO2 Induces Symmetry Breaking in Layered Dipeptide Crystals "
Angew. Chem. Int. Ed., 2023, 62, e202214184.
" Emodin-Based Nanoarchitectonics with Giant Two-Photon Absorption for Enhanced Photodynamic Therapy "
Angew. Chem. Int. Ed., 2023, 62, e2023080.
" Tunable Chirality of Self-Assembled Dipeptide Mediated by Bipyridine Derivative "
Angew. Chem. Int. Ed., 2023, 62, e202314368.
" Light-Sensitive Photosensitizer Nanoparticles for Improved Photodynamic Therapy against Solid Tumors "
Angew. Chem. Int. Ed., 2022, 61, e202210920
" Oriented Nanoarchitectonics of Bacteriorhodopsin for Enhancement of ATPGeneration of FoF1-ATPase Based Assembly System "
Angew. Chem. Int. Ed., 2022, 61, e202116220.
" Schiff Base Mediated Dipeptide Assembly toward Nanoarchitectonics "
Angew. Chem. Int. Ed., 2022, 61, e202207752.
" Boric Acid-Fueled ATP Synthesis by FoF1 ATP Synthase Reconstituted in a Supramolecular Architecture "
Angew. Chem. Int. Ed., 2021, 60,7695-7698.
" Embedment of quantum dots and biomolecules in an in‐situ formed dipeptide hydrogel using microfluidics "
Angew. Chem. Int. Ed.,2021, 60, 6798-6806.
"Co‐assembled Supramolecular Gel of Dipeptide and Pyridine Derivatives with Controlled Chirality"
Angew. Chem. Int. Ed., 2021, 60, 2099-2103.
" Acid‐Activatable Transmorphic Peptide‐Based Nanomaterials for Photodynamic Therapy "
Angew. Chem. Int. Ed., 2020, 59, 20582-20588.
"A Dipeptide‐Based Hierarchical Nanoarchitecture with Enhanced Catalytic Activity"
Angew. Chem. Int. Ed., 2020,59, 18960–18963.
"Self-Assembled Dipeptide Aerogels with Tunable WettabilitySelf-Assembled Dipeptide Aerogels with Tunable Wettabilit"
Angew. Chem. Int. Ed., 2020,59, 11932–11936.
"Nanoarchitectonics beyond Self-Assembly: Challenges to Create Bio-Like Hierarchic Organization"
Angew. Chem. Int. Ed., 2020, 59, 5424–15446.
"Reconstitution of FoF1-ATPase- based biomimetic systems".
Nat. Rev. Chem., 2019 ,3,361-374.
"Molecular Assembly of Rotary and Linear Motor Proteins".
Acc. Chem. Res., 2019, 52,1623-1631.
"Photoactive Properties of Supramolecular Assembled Short Peptides".
Chem. Soc. Rev. 2019, 48, 4387-4400.
"Cell Membrane-Covered Nanoparticles as Biomaterials".
Natl. Sci. Rev., 2019, 6, 551-561.
"Stable and optoelectronic dipeptide assemblies for power harvesting".
Mater. Today, 2019, 30, 10-16.
Prof. Junbai Li' s Author Profile .
Angew. Chem. Int. Ed., 2018, 57, 16262.
"Ultrafast Assembly of Dipeptide Supramolecular Organogels and Phase Transition from Gel to Crystal".
Angew. Chem. Int. Ed. 2019, 58, 11189-11194.
"Assembled Vitamin B2 Nanocrystals with Properties of Optical Waveguide and Photosensitivity and Their Potential Biomedical Application".
Angew. Chem. Int. Ed., 2019, 58, 7254-7258.
"Nanozyme-Catalyzed Cascade Reactions for Mitochondria-Mimicking Oxidative Phosphorylation" .
Angew. Chem. Int. Ed., 2019, 58, 5572-5576.
"Supramolecularly Assembled Nanocomposites as Biomimetic Chloroplasts for Enhancement of Photophosphorylation".
Angew. Chem. Int. Ed., 2019, 58, 796-800.
"Tuning Thiol-Based Self-Assembled Monolayer Chemistry on a Gold Surface toward Synthesis of Biochemical Fuel".
Angew. Chem. Int. Ed., 2019, 58, 1110-1114.
"Thermoresponsive Polymer Brush Modulation on the Direction of Motion of Phoretically Driven Janus Micromotors"
Angew. Chem. Int. Ed., 2019, 58, 4184-4188.
"Spontaneous Membrane Generation and Extension in a Dipeptide Single Crystal and Phospholipid Mixed System".
Angew. Chem. Int. Ed., 2018, 57, 11404-11407.
"Use of Optically Matched Semiconductor Quantum Dots to Improve Photophosphorylation of Chloroplasts".
Angew. Chem. Int. Ed., 2018, 57, 6532-6535.
"Magnetic Mesoporous Silica Nanoparticles Cloaked by Red Blood Cell Membranes: Applications in Cancer Therapy".
Angew. Chem. Int. Ed., 2018, 57, 6049-6053.
"A Photoinduced Reversible Phase Transition in a Dipeptide Supramolecular Assembly".
Angew. Chem. Int. Ed., 2018, 57,1903-1907.
"Assembled Nano-complex for Improving both Therapeutic Efficiency and Treatment Depth in Photodynamic Therapy".
Angew. Chem. Int. Ed., 2018, 57, 7759-7763.
"Charge-Induced Secondary Structure Transformation of Amyloid-Derived Dipeptide Assemblies from b-Sheet to a-Helix".
Angew. Chem. Int. Ed., 2018,57, 1537-1542.
"Quantum Confined Peptide Assemblies with Tunable Visible to Near-Infrared Spectral range".
Nature Communications, 2018, 9, 3217.
课题组简介
致力于仿生超分子化学的分子组装和纳米结构体系设计。尤其是基于生物分子磷脂,肽与蛋白的仿生分子组装和物理化学机理的研究,通过组装构建"人工细胞"。以模拟生物体结构和功能为基础,在分子水平上构建具有特殊功能的超分子组装体。重点研究旋转马达蛋白ATP合酶与线性马达蛋白Kinesin的优化重组,从多维度模拟细胞器结构与功能;探索ATP合酶在调控叶绿体的光合磷酸化和线粒体的氧化磷酸化过程中的能量合成机制,实现功能增强;研究寡肽分子尤其是苯丙氨酸的组装与解组装,结构转变调控及其光电性质的研究;通过模板组装技术构建系列功能化纳米结构体系;双光子共聚焦和超分辨荧光成像在组装体系中的应用研究。
新闻动态
瑞典皇家工程科学院院长为李峻柏研究员颁发证书 李峻柏研究员与瑞典国王(右一)和王后(右二)交谈
祝贺李峻柏研究员获得日本化学会Lectureship Award!
祝贺李峻柏研究员获得第二届中国软物质研究杰出贡献奖!
祝贺李峻柏研究员担任 Journal of Colloids and Surfaces A : Physicochemical and Engineering Aspects 主编!
祝贺李峻柏研究员获得JCIS Dasch Wasan "胶体与界面科学"杰出贡献奖!
祝贺费进波,贾怡,冯熙云,李洁龄,蔡鹏,秦晨晨荣获2015年度化学所青年科学奖优秀奖!